Statistics Canada says manufacturing sales fell 0.8% in April to $49.1 billion, the third decline in four months.
It says the biggest drops came in the aerospace product and parts industry and in petroleum and coal products.
But sales of motor vehicles rose to their highest level since November 2007.
The agency says sales fell in 13 of 21 industries, representing approximately 45% of the manufacturing sector.
Sales of durable goods decreased 0.7%, while non-durable goods sales declined 1.0%.
In constant dollars, sales declined 0.6% in April, reflecting reduced volume.
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