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Cardiome Pharma Corp.

10:45 AM EST - Cardiome Pharma Corp. : a Vancouver-based heart drug developer, says it more than doubled its annual loss to $85.5 million for 2007 from $36.1 million in 2006 as the company faced sharply lower revenues and higher research costs. Cardiome said Wednesday it lost $1.36 per common share for the year ended Dec. 31, compared with a loss of 68 cents in 2006. Cardiome Pharma Corp. shares T.COM are trading up 1 cent at $8.49.