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Lilly Sprints on New Alzheimer Treatment

Shares in Eli Lilly (NYSE: LLY) gathered momentum in early Wednesday trading, on new product developments.

The Alzheimer’s treatment donanemab, which is made by Lilly, significantly slowed progression of the mind-robbing disease, according to clinical trial data released Wednesday by the company.

Patients who received the monthly antibody infusion during an 18-month study demonstrated a 35% slower decline in memory, thinking and their ability to perform daily activities compared with those who did not receive the treatment, Eli Lilly’s data showed.

Patients who took donanemab were 39% less likely to progress to the next stage of the disease during the study, according to the trial results.

But the treatment’s benefits will have to be weighed against the risk of brain swelling and bleeding that can be serious and even fatal in rare cases. Three participants in the trial died from these side effects.

Lilly plans to apply for Food and Drug Administration approval of donanemab as soon as this quarter, according to the company. The trial studied individuals in the early stages of Alzheimer’s who had a confirmed presence of brain plaque associated with the disease.

Dr. Daniel Skovronsky, Lilly’s chief scientific and medical officer, said donanemab demonstrated the highest level of efficacy of any Alzheimer’s treatment in a clinical trial. The company is working to get donanemab approved and on the market as quickly as possible, he said.

Eli Lilly’s stock was up $16.94, or 4.2% in early trading Wednesday to $421.14.